Brenner, James
James Brenner
Associate Professor | Chemistry and Chemical Engineering
Affiliate Faculty | Biomedical Engineering and Science
Contact Information
Personal Overview
Active Research and Development
Since 2013, Dr. Brenner has specialized in maker education and on how to automate tissue engineering. Learning how to disinfect 3D printed tissue scaffolding led to a company named Chem-Free Solutions (https://www.chem-freesolutions.com), which makes an ultraviolet disinfection tile for hospitals and assisted living facilities. Unlike UV lamps, it uses six different LED's to eradicate all bacteria and viruses, instead of missing critical ones like MRSA and Clostridium difficile. That work funds his research in the tissue engineering test bed area.
He is building a bioreactor array with the full complement of traditional chemical engineering sensors, but also a cytokine sensor for detecting the inflammatory response of growing tissues when exposed to a variety of inputs. In support of the tissue engineering test bed mission, most of my research group is putting together a hybrid of a nanoparticle tracking analyzer, a confocal laser scanning microscope, a nanopositioning system, and a zeta particle analyzer to eventually watch cells move toward their eventual tissues in the presence of electric and magnetic fields, along with growth and differentiation factors.
Dr. Brenner's maker education initiative and prior nanotechnology experience is being converted into an electronic textbook for the Kern Entrepreneurial Engineering Network (KEEN).
A couple of Prof. Brenner's research students are putting together a literature review entitled "Mining, Refining, and 3D Printing a Lunar Colony".
One Ph.D. student that Prof. Brenner co-advises with Prof. Gordon Nelson (Chemistry) is developing the synthesis-structure-function relationships for flexible polyurethane foams (Think MyPillow.), after working since 2000 on rigid polyurethane foams for external tanks for the space shuttle program and for Larsen Motorsports' jet dragster's safety program.
Past Research
From 2008-2013, all but one of Dr. Brenner's research projects evolved out of his nanotechnology education research and shifted much more toward biomedical applications of nanotechnology.
- self-assembly of a range of nanomaterials including zeolites, protein fibers characteristic of Alzheimer's disease, and ammonium hydrogen phosphate;
- uric acid crystallization and its effects on osteoporosis and gout;
- improved syntheses of nanomaterials with emphases on narrow particle and pore size distributions;
- electrical and colorimetric biosensing with modified gold nanoparticles;
- genetic modification using a gene gun and modified gold nanoparticles; and
- development of a hybrid of 3-D printing (rapid prototyping) and electrospinning for inexpensive, yet precise "printing" of tissue scaffolding.
The one non-nano project Dr. Brenner worked on during that time involved environmental testing chambers for collection of mechanical property data for materials under extreme (cryogenic or very high temperature, controlled atmosphere, cyclic fatigue, corrosion (including with salt water), AND/OR creep) conditions. He was looking to determine the root cause of failures under situations where multiple possible failure mechanisms are possible.
At Florida Tech from 1998-2008, Prof. Brenner worked in the following areas:
- hydrogen purification and sensing;
- molecularly imprinted polymer-based sensing; and
- nanotechnology education
The hydrogen work led to a now defunct company named Florida Syngas that converted a variety of waste hydrocarbons into chemicals through a carbon monoxide and hydrogen mixture called syngas as an intermediate. When then presidential candidate Barack Obama wooed his customers to absolve their environmentalist guilt with tax incentives for solar energy, Dr. Brenner left the energy business, very reluctantly.
After continuing similar work to his Ph.D. work, as well as some work in the area of nanotechnology while a postdoc at Argonne National Laboratory, Prof. Brenner worked at Westinghouse Savannah River Company (WSRC) in the area of hydrogen storage using metal hydrides, another class of interstitial compounds. His key development during his work at WSRC was the use of metallic foams, a new class of porous metals, as media for the enhancement of heat transfer into and out of hydrogen storage beds. Such a development was critical for our nation's tritium mission (Tritium is a nuclear isotope of hydrogen.), but if hydrogen vehicles were to become a reality, cutting down the time for refueling to a reasonable time, as this heat transfer improvement enabled, was critical.
M.S. and Ph.D. in Chemical Engineering from The University of Michigan under Prof. Levi Thompson, with work focusing on development of catalysts for hydrodesulfurization and hydrodenitrogenation of crude oil. Since the start of Dr. Brenner's graduate work, the key themes of his work are:
- development and characterization of novel porous materials;
- applications involving interstitial compounds; and
- characterization and applications development involving interactions of molecules with surfaces.
During this time, Prof. Brenner became an expert in a number of areas of materials characterization including Fourier transform infrared spectroscopy of molecules adsorbed (sticking) to surfaces and temperature-programmed desorption of these molecules, residual gas analysis of molecules desorbed from surfaces, chemisorption and physisorption, pore and particle size distribution analysis, surface area measurements, and scanning and transmission electron microscopies. Prof. Brenner's synthesis expertise during this time was in the development of porous, high surface area metal nitrides and carbides, which are interstitial compounds.
B.S. in Chemical Engineering from the University of Delaware
- Monte Carlo simulation of depolymerization of lignin (wood), the first step in papermaking.
- Monte Carlo simulation of hydrogenated amorphous silicon thin film semiconductors, followed by an analysis of how synthesis conditions affected film properties and device performance.
Educational Background
Ph.D., ChE, The University of Michigan, 1994
M.S., ChE, The University of Michigan, 1991
B.S., ChE, The University of Delaware, 1989
Professional Experience
May, 2008-current, Director of Chemical Engineering on Board of Advisors, Florida Syngas, Inc.
Vice President for Sensor Development, Meditech Fefer, 2001.
Senior Engineer, Westinghouse Savannah River Company, Process Technology Group, Chemical & Hydrogen Technology, 1997-1998.
Postdoctoral Research Chemist, Argonne National Laboratory, 1994-1997.
Current Courses
CHE 1101 Introduction to Chemical Engineering I (process engineering)
CHE 1102 Introduction to Chemical Engineering II (spreadsheet calculations, curve fitting, plotting)
CHE 3260 Introduction to Materials Science and Engineering
CHE 3265 Materials Science and Engineering Laboratory
CHE 1091 Nanoscience and Nanotechnology Lab I
CHE 5567 Nanotechnology
CHE 5569 Biomaterials and Tissue Engineering
CHE 4568 Materials Characterization Laboratory
CHE 4566 Nanotechnology Laboratory 2
CHE 4288 Petroleum Refining
CHE 5252 Catalytic Reactor Design
Selected Publications
Development of a Passively Cooled, Electrically Heated Hydride (PACE) Bed. J.E. Klein, J.R. Brenner, and E.F. Dyer, Fusion Science and Technology 41 (2002) 782-787.
High Performance Polyimide Foams. M.K. Williams, G.L. Nelson, J.R. Brenner, E.S. Weiser, E.S., and T.L. St.Clair, ed. by G.L. Nelson and C.A. Wilkie, in ACS Symposium Series #797/Fires and Polymers: Materials and Solutions for Hazard Prevention, American Chemical Society/Oxford Press (2001) 49-62.
Microstructural Characterization of Highly HDS-Active Co6S8-Pillared Molybdenum Sulfides. J.R. Brenner, C.L. Marshall, L. Ellis, N. Tomczyk, J. Heising and M.G. Kanatzidis. Chem. Mater. 10 (1998) 1244-1257.
Recognition & Awards
2001-2002 and 2002-2003 College of Engineering Teacher of the Year (as voted by students)
2005-2006 Educator of the Year (university-wide);
Alpha Phi Teacher of the Year in 2006-2007;
university-wide award of Teacher of the Year by the Future Educators of America in 2002 and in 2007.
College of Engineering Teacher of the Year by the College of Engineering in 2009
Kerry Bruce Clark Award for Excellence in Teaching by the Florida Tech Faculty Senate in 2010.
April, 2007-March, 2008. Florida Tech Faculty Senate President including the following awards: Gavel Award for Distinguished University Service in 2008 and the College of Engineering's Service Award in 2008.
Oct. 1997-July, 1998, Westinghouse Savannah River Co. Vice President's Award
Research
Since 2008, all but one of Dr. Brenner's research projects have evolved out of his nanotechnology education research and has shifted much more toward biomedical applications of nanotechnology.
- self-assembly of a range of nanomaterials including zeolites, protein fibers characteristic of Alzheimer's disease, and ammonium hydrogen phosphate;
- uric acid crystallization and its effects on osteoporosis and gout;
- improved syntheses of nanomaterials with emphases on narrow particle and pore size distributions;
- electrical and colorimetric biosensing with modified gold nanoparticles;
- genetic modification using a gene gun and modified gold nanoparticles; and
- development of a hybrid of 3-D printing (rapid prototyping) and electrospinning for inexpensive, yet precise "printing" of tissue scaffolding.
The one non-nano project Dr. Brenner is working on involves environmental testing chambers for collection of mechanical property data for materials under extreme (cryogenic or very high temperature, controlled atmosphere, cyclic fatigue, corrosion (including with salt water), AND/OR creep) conditions. He is looking to determine the root cause of failures under situations where multiple possible failure mechanisms are possible.