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Gu, Linxia

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Linxia Gu

Professor | Biomedical Engineering and Science

Department Head | Biomedical Engineering and Science

Affiliate Faculty | College of Engineering and Science - Mechanical and Civil Engineering

Contact Information

gul@fit.edu
(321) 674-8447
Gordon L. Nelson Health Sciences- 132
Google Scholar
Research Website

Expertise

Stent optimization, Abusive head trauma, Ocular injury, Mutiscale materials characterization, Simulation-driven AI/ML

Personal Overview

Dr. Linxia Gu moved to Florida Institute of Technology in August 2019. Prior to this, she was a Professor of the Department of Mechanical and Materials Engineering at the University of Nebraska-Lincoln, where she rose through the ranks of Assistant Professor, Associate Professor with Tenure, and Professor. She received her Ph.D. degree in mechanical engineering from the University of Florida in December 2004. Dr. Gu’s research expertise lies in the biomechanics and biomaterials using both computational and experimental methods. The specific application areas include vascular mechanics and indirect traumatic injury to the brain and eye. Her group is particularly interested in developing multi-scale multi-physics models to study and exploit tissue responses and cellular mechanotransduction, and to gain new mechanistic insights into the interplay of mechanics and human body. The multidisciplinary effort has resulted in > 130 journal papers, and $11 million research funding from NIH, NSF, ARO, and NASA. She is an elected fellow of ASME, a recipient of NSF CAREER award and UNL Edgerton Innovation research award.

Educational Background

Ph.D., Mechanical Engineering, University of Florida

M.E., Mechanical Engineering, Dalian University of Technology

B.E., Mechanical Engineering, Xi’an Jiaotong University

Professional Experience

  • 08/2019-present
    • Professor, Biomedical Engineering/Mechanical Engineering Joint appointment, FIT
  • 08/2019-08/2020
    • Adjunct Professor, Mechanical and Materials Engineering, University of Nebraska-Lincoln (UNL)
  • 03/2019
    • Promoted to Professor, effective as of 08/2019, Mechanical and Materials Engineering, UNL
  • 08/2013-08/2019
    • Associate Professor, Mechanical and Materials Engineering, UNL
    • Area Chair of Biomedical Engineering
  • 11/2013-11/2016        
    • Graduate Chair for the Biomedical Engineering PhD program, College of Engineering, UNL
  •  06/2009-08/2019
    • Faculty Associate, Nebraska Center for Materials and Nanoscience(NCMN) & Center for Advanced Surgery Technology (CAST), U. Nebraska-Medical Center (UNMC)
  • 01/2009-08/2013 
    • Assistant Professor, Mechanical and Materials Engineering, UNL
  •  08/2006-12/2008
    • Assistant Professor, Mechanical Engineering, SDSM&T

Current Courses

Undergraduate

  • Capstone Design
  • Elements of Machine Design
  • Mechanical Engineering Design I
  • Advanced Machine Design
  • Statics
  • Mechanics of Solid
  • Biomechanics

Graduate

  • Mechanics of Biomaterials (Developed New Course)
  • Vascular Mechanics (Developed New Course)

Selected Publications

  1. Lin, S. M., Lampi, M.C., Reinhart-King, C., Tsui, G.C.P., Wang, J., Nelson, C.A., and Gu, L.X., 2018. Eigenstrain as a Mechanical Set-Point of Cells. Biomechanics and Modeling in Mechnobiology. 17(4), 951-959. DOI: 10.1007/s10237-018-1004-0   
  2. Hua*, Y., Wilson*, C.L., Lin, S.M., Dutta, D., Kidambi, S., Gu, L.X., 2018. Traumatic Injury of Astrocytes: An In Vitro Study. Journal of Mechanics in Medicine and Biology, 18(4), 1850040 (16 pages). DOI: 10.1142/S0219519418500409 (* Equal Contribution)
  3. Lin, S. M., Han, X.W., Bi, Y.H., Ju, S.Y., and Gu, L.X, 2017. Fluid-Structure Interaction in Abdominal Aortic Aneurysm: effect of modeling techniques. BioMed Research International,  Article ID 7023078, 10 pages. DOI: 10.1155/2017/7023078
  4. Lin, S. M., Han, X.W., Tsui, G.C.P., Hui, D., and Gu, L.X., 2017. Active Stiffening of F-Actin Network Dominated by Structural Transition of Actin Filaments into Bundles. Composites Part B-Engineering, 116, 377–381. DOI: 10.1016/j.compositesb.2016.10.079
  5. Hölzl, K.*, Lin, S.M.*, Tytgat, L., Van Vlierberghe, S., Gu, L.X., and Ovsianikov, A., 2016. Bioink Properties Before, During and After 3D Bioprinting. Biofabrication. 8(2016) 032002, DOI: 10.1088/1758-5090/8/3/032002  (* Equal Contribution)
  6. Zhao, S., and Gu, L.X., 2014. Implementation and Validation of Aortic Remodeling in Hypertensive Rats. Journal of Biomechanical Engineering-Transactions of the ASME, 136(9), 091007 (8 pages). DOI: 10.1115/1.4027939
  7. Hua, Y., Akula, P., Gu, L.X., Berg, J., and Nelson, C.A., 2014. Experimental and Numerical Investigation of the Mechanism of Blast Wave Transmission through aSurrogate Head, Journal of Computational and Nonlinear Dynamics-Transactions of the ASME, 9(3), 031010 (9 pages). DOI: 10.1115/1.4026156
  8. Zhao, S., Gu, L.X., and Froemming, S.R., 2012. On the Importance of Modeling Stent Procedure for Predicting Arterial Mechanics. Journal of Biomechanical Engineering- Transactions of the ASME, 134, 121005 (6 pages). DOI: 10.1115/1.4023094.

Recognition & Awards

  • Fellow of American Society of Mechanical Engineers (2016) in the category of Research and Development
  • Edgerton Innovation Award (2013), UNL College of Engineering
  • NSF Faculty Early Career Development (CAREER) Award (2013)
  • Faculty Service Award (2015), UNL College of Engineering
  • Outstanding Service Award (2014), Material and Nanoscience Educational Outreach, Nebraska Center for Materials and Nanoscience.
  • Recognition for Contribution to Students, UNL Teaching Council and Parents Association, Academic Year 2009-10 & 2010-11
  • Three-in-Five Competition award: “Mobility-Enhancing Fall-Prevention Device for Physical Rehabilitation”, 2014 Design of Medical Devices (DMD) Conference.
  • Keynote lecture (2015) titled “Mechanics of Artery Remodeling”, The 23st International Conference on Composites/Nano Engineering (ICCE-23), Chengdu, China, 2015.
  • Most read paper as featured in Biofabrication website and the corresponding twitter (2018-3-23); also included in a special issue on bioinks (2018-12): “Bioink properties before, during and after 3D bioprinting”. 
  • Featured in Pocket Science of Nebraska Today (2017): “Controllable Energy Absorption of Double Sided Corrugated Tubes under Axial Crushing”.
  • Featured in Biomedical Advances (2017): “Fluid-Structure Interaction in Abdominal Aortic Aneurysm: effect of modeling techniques” because of its innovation and potential for significant impact.
  • Featured by U.S. Medicine, BTN LiveBig (2015): “Relevance of Blood Vessel Networks in Blast-Induced Traumatic Brain Injury” shed new light on how roadside bomb explosions injure the brain
  • Featured by NSF Discovery and NSF Science 360 News Service (2014): study on cell and tissue alternations following stent implantation
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